C3 Complement TestC3 Complement Test

C3 Complement Test

C3 Complement Test provides information about your immune system. It shows how parts of your immune system are responding. to harmful substances. This test can help your health cove ponder diagnose autoimmune disorders (like Lupus), as well as other conditions. C3 is a type of protein and a part of the complement system in our blood-complement system. made up of 30 provides proteins that play an important part in our immune system and fight against microorganisms. at is very important and is in high numbers C3 helps in Killing microbes.

Function OF C3:

It is a group of proteins that work together to destroy foreign invaders (such as bacteria, and viruses), trigger inflammation, and remove debris from cells and tissues.

Normal Ranges of C3 Test:

Normal Value of C3 Compliment Test is: (88 to 206 mg/dL or 0.8 to 1.6g/L).

Is This Test Have Other Name:

It is also called Component 3 Test and Also called C3 test.

Purpose of C3 Test:

A C3 complement test is used to measure a protein called C3, which is part of body’s immune response. High or low value may indicates medical problems. ranging from autoimmune diseases and immune disorders. to infections and chronic kidney or liver disease.

Signs OF C3 Test:

  • It may be Heart attack (myocardial Infarction)
  • Or heart problem
  • Sarcoidosis (inflammatory disease)
  • Some types of Cancer
  • Thyroid disease
  • Ulcerative colitis
C3 Complement Test

Causes of High C3 Complement Value:

  • After injury.
  • After Microbial Infections.
  • Ulcerative colitis.
  • Thyroid disease.
  • Cancer.

Causes OF Low C3 Complement Value:

  • SLE (Systemic Lupus Erythematosus)
  • Recurrent Infections
  • Lupus Nephritis or Rheumatoid Arthritis
  • Kidney and liver failure
  • Organ transplant Rejection
  • Malnutrition
  • Hepatitis A, B and C
  • Septicemia (blood poisonings)
  • Hemolytic anemia and hereditary angioedema

How to Perform This Test:

Blood sample needed Fasting Condition.


Collect the blood Sample 3 to 5 ml in a Gel tube or Red top Tube after 10 hours of fasting condition. Take the blood sample and then Centrifuge the sample. After centrifugation, the first step is to heat the serum to destroy the patient’s complement. And then a measured amount of complement and antigens are then added to the serum in the patient’s serum the complement is fined by reaction with the antigen-antibody complexes in patient B serum. There are no antibodies to the complex with antigen and the compliment. The Serum turns a pink color.

Interpreting the Results:

The C3 test is measured in mg/dL of the value is to normal ranges may vary slightly among different laboratories.

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