Aspergillosis Disease, Aspergillus Lives in the environment. of all the fungi that cause disease in human hosts, none is as widely distributed in nature as members of the genus Aspergillus. They are found where organic debris occurs, especially in soil, decomposing plant matter, household dust, building material, some foods, and water. It is very common indoors, and outdoors, so most people breathe in fungal spores every day. It is almost impossible to avoid daily inhalation of Aspergillus spores. In People with a healthy immune system. Aspergillus fungi do not cause disease. However, infection results when healthy immune function deteriorates.
Signs and Symptoms of Aspergillosis:
- Chest Pain.
- Cough and wheezing.
- Shortness of breath.
- Weigh loss
- That disseminates to
- Bone or Skin
Mode of Transmission of Aspergillosis:
Transmission: Aspergillus fumigatus is Primarily transmitted:
- Through the inhalation of fungal spores.
- Indoor environment.
- Outdoor environment
- Direct Skin contact.
Laboratory Diagnosis of Aspergillosis depends on:
- Fungal culture
- Direct examination of Pathological specimens
Treatment of Aspergillosis:
Treatment is with:
- Voriconazole and Itraconazole
Another medicine that can be used is Amphotericin B However, successful therapy depends on the treatment of the underlying disease so host resistance increases 14 Antifungal Drugs.