MPV (Mean Platelet Volume)

MPV (Mean Platelet Volume)

MPV (Mean Platelet Volume), The mean platelet volume (MVP) is the average size of your Platelet. When the MPV value is high in blood and platelet count is low, it means that the bone marrow is producing platelets quickly due to increased destruction of platelets. Low MPV means your platelets are similar in size, which means older platelets are in circulation, which means your bone marrow is not producing enough new platelets.

Purpose of Mean Platelet Volume(MPV)

This parameter is used to know about platelet size, function, and activation.

Normal Value of MPV in blood

  • 8.5 to 12 FL (Femto Liter)

MPV Calculation

MVP = Platelecrit divided by Platelet Count

Causes of High MPV (Mean Platelet Volume)

  1. Hyperthyroidism
  2. Heart disease
  3. Atrial Fibrillation
  4. Diabetes
  5. High blood pressure
  6. Stroke
  7. Vitamin D deficiency
  8. Certain Cancers
  9. Hypothyroidism

Causes of Low MPV

  1. Aplastic Anemia
  2. Inflammatory Bowel Disease
  3. Cytotoxic chemotherapy
  4. Enlarged deficiency anemia
  5. Iron deficiency anemia
  6. Crohn’s disease
  7. Ulcerative colitis
  8. Reactive Thrombocytosis

Specimen Collection for MPV Test

  • Collect 3 to 5 ml of blood in an EDTA tube.
  • The test will be performed by using an automated cell counter or by formula

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