Anti insulin Antibody Test
Anti insulin Antibody Test, Anti Insulin Antibodies are Antibodies that are Produced by our body against Insulin taken by patients for the treatment of diabetes. When the insulin is injected into the patient’s body then the antibodies are combined with Some of the insulin, leaving less insulin for glucose metabolism. As a result, the patient increases the amount of insulin. Then, this process is called insulin resistance In insulin-resistant bodies cells do not respond to insulin. The anti-insulin antibody test checks to see if your body has produced antibodies against insulin. Antibodies are proteins the body producers to protect itself when it detects anything ”foreign” such as a virus or a transplanted organ.
Types of Anti Insulin Antibody:
(1) IgG (most common)
(2) IgM (Less common)
(2) IgE (Associated with Allergy)
Causes of Anti-Insulin Antibody:
- Especially too much fat in the abdomen and around organs called (visceral fat)
- HLA-type delivery route
- Exposed to beef or pork insulin
Normal Range of Anti-Insulin Antibody in blood:
- Negative <95nu/mL
- Borderline 95-124 nu/mL
- Positive >125 nu/mL
- Less than 3%.
- If above 3%. it is considered that Andi insulin Antibodies are present in the blood against insulin.
Causes of High Anti Insulin Antibody in blood:
- Insulin Allergy
- Insulin Resistance (This condition in which cells in muscles, fats, and life does not respond to inulin due to which Hypoglycemia occurs).
Diagnostic Importance of Anti-Insulin Antibody:
- To diagnose insulin resistance
- To screen for insulin allergy
- To elevate that hypoglycemia is caused by overuse of inulin
How to perform the test?
Procedure:
Collect the 3 to 5ml blood in a Red top tube. Centrifuge the blood sample and separate the serum. Use the serum for the test in the advanced analyzer. This test may be performed if You have or are at risk for type 1 diabetes. You appear to have an allergic response to the insulin you are taking insulin to Control your diabetes, and your blood sugar level varies a lot.
Risks factors:
- Excessive bleeding
- Fainting feeling light-headed
- Multiple punctures to locate veins
- Hematoma (blood building up under the skin)
- Infection (a slight risk any time the skin is broken)
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