Cardiolipin AntibodiesCardiolipin Antibodies

Cardiolipin Antibodies

Cardiolipin Antibodies are a type of fat or phospholipid important for blood clotting, present in platelets and cell membranes of cells in the blood. It helps to investigate inappropriate blood clot formation, to help determine the cause, of recurrent miscarriage, as a painting of an evaluation for antiphospholipid syndrome. Cardiolipin antibodies. are also associated with thrombocytopenia, recurrent miscarriage (especially 2nd, 3rd trimesters) and with premature labor, and pre-eclampsia. Autoantibodies produce against Cardiolipin by our immune system mistakenly and cause abnormal blood clotting.

Types Of Cardiolipin Antibodies:

  • IgG
  • IgM
  • IgA

Causes of High Cardiolipin Antibodies:

  • Excessive blood clot formation
  • Thrombosis
  • Abnormal blood clotting
  • Miscarriages
  • Systemic Lupus Erythematosus.
  • Thrombocytopenia
  • Pre- Eclampsia
  • Epilepsy
  • Chorea
  • Antiphospholipid Antibody Syndrome (APS) most commonly SLE.

Other Name Of Cardiolipin Antibodies:

It is also called Anticardiolipin Antibodies Test.

Diagnostic Importance of Cardiolipin:

  • It help cause of abnormal blood clotting or Thrombosis.
  • To help diagnose cause of recurrent Miscarriages.
  • To diagnose Anti phospholipid Antibody syndrome and systemic Lupus Erythematosus.
Cardiolipin Antibodies

Normal Range Of Cardiolipin Antibodies:

  • IgG Less than 15 GPL Units
  • IgM Less than 12 MPL Unit
  • IgA Less than 12 APL Units

How To Perform The Test:

Blood Sample required.


  • Collect 3 to 5ml blood sample in Red Top Tube or Gel Tube.
  • Centrifuge the blood Sample.
  • After centrifugation collect the serum and further test is performed and run on Elisa or any other advance Analyzer.
  • And check the antibodies Level.

Result Interpretation:

If you are negative for cardiolipin antibodies, that is normal. If you are positive, you might have cardiolipin antibodies Syndrome.

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