CA-125 Cancer Antigen

CA-125 Cancer Antigen (CA-125) is a protein found in Ovarian Cancer cells. A CA-125 blood test measures the amount of cancer antigen 125 in the bloodstream. The protein is produced by the cells and can be found in the blood. A CA-125 test may be used to monitor certain Cancers during and after treatment. CA-125 test may be used for an early sign of ovarian cancer, in people with a very high risk of the disease. In this process CA-125 test is used to check the recurrence of cancer Treatment Should result in decreased levels, elevated Levels may indicate the recurrence of Cancer. Because the test is affected by many other problems. About 20% of the women with Ovarian cancer have a negative test then the test is not used for widespread Screening for ovarian Cancer, In healthy women the Level of CA-125 is usually less than 35 units per milliliter (U/ml). While Some Women do have a naturally high level of CA-125 in their blood.

Causes Of CA-125:

  • Non cancerous growth in the uterus, such as uterine fibroids
  • Endometriosis
  • Pelvic inflammatory disease, which is a disorder in uterus, fallopian tube
  • Pregnancy first two trimesters Menstruation, endometrial and fallopian tube Cancers Ruptured ovarian cyst

Symptoms OF CA-125:

  • Loss of Appetite
  • Persistent bloating
  • Pelvic and Abdominal pain
  • Difficulty in eating
  • Increased abdominal size
  • Constipation
  • Pain during Sex
  • Back Pain
  • Fatigue

What is the Reason for the Test?


  • Ovarian Cancer
  • Other types of of Cancer
  • To find out the effectiveness of Cancer treatment

Normal Range OF CA-125:

Less than 35 U/mL.

High CA-125 Causes:


How to Perform Test?

Blood Sample taken.

How is a CA-125 Blood Test Performed:

A CA-125 blood test involved taking a blood sample torn kit was , typically from a vein in the arm. First a healthcare provider will clean and and disinfect area with an antiseptic. Then they will wrap an tornikit elastic band around the upper arm and your vein swell with blood. Insert the needle into the vein and then they will collect the blood into the Small tube attached to the needle- After enough blood has been drawn, they’ll remove the needle and cover the area will Cotton or Swap to stop any bleeding. The blood sample Sent to the laboratory for further analysis.


If your CA-125 level is higher than expected you may have a condition that isn’t cancerous or the test result could have ovarian, meaning that you have ovarian, endometrial, or fallopian tube cancer. If the level of a have-not is less than 35 you have not Cancerous.

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